Rescue IVM using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes

Paulsen B, Piechota S, Barrachina F, Giovannini A, Kats S, Potts KS, Rockwell G, Marchante M, Estevez SL, Noblett AD, Figueroa AB, Aschenberger C, Kelk DA, Forti M, Marcinyshyn S, Wiemer K, Sanchez M, Belchin P, Lee JA, Buyuk E, Slifkin RE, Smela MP, Fortuna PRJ, Chatterjee P, McCulloh DH, Copperman AB, Ordonez-Perez D, Klein JU, Kramme CC. Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes. J Assist Reprod Genet. 2024 Aug;41(8):2021-2036. doi: 10.1007/s10815-024-03143-4. Epub 2024 May 30. PMID: 38814543; PMCID: PMC11339229.